What is PGD?
Preimplantation genetic diagnosis (PGD) is a procedure introduced during the 1980’s as a way to screen embryos for sex-linked chromosomal disorders or single-gene defects. PGD is a highly sophisticated procedure that is offered by a restricted number of facilities. In Mexico, PGD for gender selection has become a popular option for couples keen on choosing the gender of their children.
PGD can meticulously screen over 50 genetic diseases, including Cystic fibrosis, Down syndrome, and Hemophilia A and B.
Gender selection with PGD is piloted during in vitro fertilization (IVF) in Mexico. While the genetic assembly XX produces a female child, the XY arrangement encompasses a male. Your fertility specialist in Mexico transfers the embryos of the desired sex into the uterus.
Infertility treatment can be a challenging time, emotionally and physically. Patients who conceive through successfully infertility treatment cycles desire the assurance of a healthy pregnancy. Pre-implantation genetic diagnosis in Mexico sanctions intended parents to screen embryos to check for chromosomal abnormalities or inherited disease before IVF takes places.
A Good Candidate for PGD
Undergoing fertility treatments can be a high mountain to climb. IVF clinics in Mexico give Intended parents strength and are committed and supportive throughout the process. Communication is key.
PGD may be optional for:
- Couples who have had a previous birth of a child with a single-gene defect, such as cystic fibrosis, sickle cell anemia and Huntington disease.
- Couples who have a family history of diseases, which are passed to the child through the mother. Recessive disorders include hemophilia and most neuromuscular dystrophies. Dominant disorders include Rhett syndrome and vitamin D–resistant rickets.
- Couples in which both partners are "carriers" and are at risk for passing on inherited genetic disease to their offspring.
- Women of advanced reproductive age and couples who have had recurrent pregnancy loss due to chromosomal aneuploidy.
- Intended parents who wish to select the gender of their child. The ability to determine the babies sex and notify the parents during the PGD process is legal in Mexico but illegal in many other countries.
Currently fluorescent in situ hybridization or FISH is the most prevalent PGD technique used in Mexico. FISH attains the number of certain chromosomes and observes their flow. PGD in Mexico can determine if an embryo has two X chromosomes (a girl) or an X and Y chromosome (a boy).
Each chromosome embraces a pattern of DNA. When a fluorescent analysis is placed on a cell, the cell can then be identified. The overall accuracy is over 90%. With Mexico’s scientifically refined equipment, the IVF with PGD method has helped many couples conceive a healthy baby, free of abnormalities or any hereditary diseases.
Risks and Side Effects of PGD
PGD in Mexico acclaims the removal of only one cell out of the embryo for gender determination, so family balancing patients do not have to worry about more cells being removed thus reducing the chances for pregnancy. Some fertility clinics in the past consistently remove more than one cell in their embryo biopsies, for medical or genetic reasons.
Inherent in any IVF procedure are risks supplementary with the use of hormones to stimulate ovulation and the potential for an ectopic pregnancy.
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by Brandie Umar