IVF with PGD - Selecting healthy embryos for IVF treatment


Infertility treatment can be a difficult procedure emotionally and physically. Patients who conceive through successfully infertility treatment cycles want to be sure that the pregnancy and baby will be healthy. Pre-implantation genetic diagnosis allows parents to screen embryos to check for chromosomal abnormalities or inherited disease before IVF implantation.

Reasons for IVF with PGD

Pre-implantation genetic diagnosis allows couples to prevent genetic diseases being inherited by children.   Many couples seek fertility treatment to prevent inherited genetic diseases being passed down to their children. Before the development of pre-implantation genetic diagnosis, patients who wanted to avoid their children inheriting diseases had to rely on the use of sperm and egg donation. PGD helps patients become biological parents without the risk of severe inherited disease.

Chromosomal abnormalities are the cause of many miscarriages in otherwise healthy women. If the fertility specialist screens the embryos for the abnormality, embryos free from the defective chromosome can be used for IVF implantation.

IVF treatment often results in multiple pregnancies due to an increased number of embryos implanting into the uterus than during a natural implantation. With PGD, the healthiest embryos are chosen for implantation meaning fertility specialists can implant fewer embryos without reducing the success rate of pregnancy.

Infertility specialists can utilize PGD to identify the sex of embryos. Combining IVF treatment with pre-implantation identification of gender can help couples whose children are at risk of inherited gender based diseases. 

How does PGD work?

PGD works by identifying the male and female chromosomes in sperm. If fertilizing sperm contains a higher percentage of female (X) than male (Y) chromosomes, the chance of the baby being a girl increases. More male chromosomes increases the chance of a baby being a boy. By individually screening sperm and identifying those with dominant chromosomes, fertility clinics can help couples prevent inherited disease and balance the genders of their family.